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Glossary

Hyperkeratosis

Hyperkeratosis is a thickening of the outermost layer of the skin (stratum corneum) due to excessive production of keratin. It can be a protective reaction of the skin or a symptom of various skin diseases.

Types

  • Mechanical hyperkeratosis (protective reaction): caused by pressure, friction or mechanical load – e.g. calluses, callosities and corns.
  • Pathological hyperkeratosis: caused by skin diseases or genetic factors – e.g. psoriasis, ichthyosis or actinic keratosis (caused by UV radiation).

Symptoms

  • thickened, rough areas of skin
  • cracks or fissures, especially on hands and feet
  • pain or tenderness (e.g. with calluses or corns)
  • scaling or discolouration of the skin

Treatment

  • mechanical removal: gentle filing (pumice stone, callus file) or podiatric treatment for heavy callus or pain
  • care products: keratolytic creams with urea or salicylic acid, moisturising and rich creams
  • medical therapy for pathological forms (dermatology)

More in our guide Cracked heels and calluses.

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